Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial

Mallewa, Jane; Szubert, Alexander J; Mugyenyi, Peter; Chidziva, Ennie; Thomason, Margaret J; Chepkorir, Priscilla; Abongomera, George; Baleeta, Keith; Etyang, Anthony; Warambwa, Colin; Melly, Betty; Mudzingwa, Shepherd; Kelly, Christine; Agutu, Clara; Wilkes, Helen; Nkomani, Sanele; Musiime, Victor; Lugemwa, Abbas; Pett, Sarah L; Dangarembizi, Mutsa Bwakura-; Prendergast, Andrew J; Gibb, Diana M; Walker, Sarah A.; Berkley, James A

Effect of ready-to-use supplementary food on mortality in severely immunocompromised HIV-infected individuals in Africa initiating antiretroviral therapy (REALITY): an open-label, parallel-group, randomised controlled trial

Mallewa, Jane; Szubert, Alexander J; Mugyenyi, Peter; Chidziva, Ennie; Thomason, Margaret J; Chepkorir, Priscilla; Abongomera, George; Baleeta, Keith; Etyang, Anthony; Warambwa, Colin; Melly, Betty; Mudzingwa, Shepherd; Kelly, Christine; Agutu, Clara; Wilkes, Helen; Nkomani, Sanele; Musiime, Victor; Lugemwa, Abbas; Pett, Sarah L; Dangarembizi, Mutsa Bwakura-; Prendergast, Andrew J; Gibb, Diana M; Walker, Sarah A.; Berkley, James A

URI: http://41.89.205.12/handle/123456789/2612

Date: 2018

Abstract:

In sub-Saharan Africa, severely immunocompromised HIV-infected individuals have a high risk of mortality during the first few months after starting antiretroviral therapy (ART). We hypothesise that universally providing readyto- use supplementary food (RUSF) would increase early weight gain, thereby reducing early mortality compared with current guidelines recommending ready-to-use therapeutic food (RUTF) for severely malnourished individuals only.