Abstract:
Recent Mpox (Monkeypox) cases in Kenya, particularly in Busia County bordering Uganda, highlight challenges
in cross-border infectious disease control. Despite its increasing prevalence, research and awareness of Mpox remain
limited, with misinformation hindering prevention efforts. This study assessed the effectiveness of cross-border healthcare
collaboration in Mpox response, focusing on surveillance, challenges, and strategies for improvement. Using a descriptive
cross-sectional approach, 200 healthcare workers (100 from Kenya, 100 from Uganda) were selected via stratified random
sampling. Data were collected through structured questionnaires and analyzed using R software, employing descriptive
statistics and chi-square tests. Findings revealed that 55.6% of respondents believed Kenya and Uganda share resources
fairly, while border health posts were viewed as similarly effective in both countries. However, a lack of trained personnel
was a major barrier, cited by 30% of Kenyan and 28% of Ugandan respondents. Additionally, 75% supported
infrastructure improvements and enhanced border health monitoring for better Mpox control. Despite existing
collaboration, poor infrastructure, insufficient funding, and corruption weaken its effectiveness. Communication and data
exchange remain limited, and gender disparities exist in healthcare roles. While border health posts aid Mpox detection,
gaps persist in contact tracing and community engagement. The study recommends strengthening Kenya-Uganda
agreements for standardized Mpox response, investing in digital surveillance technologies, training healthcare personnel,
and utilizing mobile health solutions for improved reporting and case tracking.