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Browsing by Author "Injera, Wilfred E."

Browsing by Author "Injera, Wilfred E."

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  • A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost effective manner 
    Boltz, Toni A; Chu, Benjamin B; Liao, Calwing; Sealock, Julia M; Ye, Robert; Majara, Lerato; Fu, Jack M; Service, Susan; Zhan, Lingyu; Medland, Sarah E; Chapman, Sinéad B; Rubinacci, Simone; DeFelice, Matthew; Grimsby, Jonna L; Abebe, Tamrat; Alemayehu, Melkam; Ashaba, Fred K; Atkinson, Elizabeth G; Bigdeli, Tim; Bradway, Amanda B; Brand, Harrison; Chibnik, Lori B; Fekadu, Abebaw; Gatzen, Michael; Gelaye, Bizu; Gichuru, Stella; Gildea, Marissa L; Hill, Toni C; Huang, Hailiang; Hubbard, Kalyn M; Injera, Wilfred E.; James, Roxanne; Joloba, Moses; Kachulis, Christopher; Kalmbach, Phillip R; Kamulegeya, Rogers; Kigen, Gabriel; Kim, Soyeon (2024-09-09)
    We deployed the Blended Genome Exome (BGE), a DNA library blending approach that generates low pass whole genome (1-4x mean depth) and deep whole exome (30-40x mean depth) data in a single sequencing run. This technology ...
  • Immunopathological Features Developing in the Mosquito Midgut after Feeding on Anopheles gambiae Mucin-1 / Interleukin-12 cDNA Immunized Mice 
    Injera, Wilfred E.; Kabiru, Elphantus W.; Gicheru, Michael M.; Githure, John I.; Beier, John C. (Universidad de La Frontera, 2013)
    The mosquito midgut is the organ into which the blood meal passes and in which, within a peritrophic membrane secreted by the epithelium, the blood is retained during digestion and absorption. The mosquito midgut is lined ...
  • Low-coverage sequencing cost-effectively detects known and novel variation in underrepresented populations 
    . Martin, Alicia R; Atkinson, Elizabeth G.; Chapman, Sine´ad B.; Stevenson, Anne; Stroud, Rocky E.; Abebe, Tamrat; Akena, Dickens; Alemayehu, Melkam; Ashaba, Fred K.; Atwoli, Lukoye; Bowers, Tera; Chibnik, Lori B.; Daly, Mark J.; DeSmet, Timothy; Dodge, Sheila; Fekadu, Abebaw; Ferriera, Steven; Gelaye, Bizu; Gichuru, Stella; Injera, Wilfred E.; James, Roxanne; Kariuki, Symon M.; Kigen, Gabriel; Koenen, Karestan C.; Kwobah, Edith; Kyebuzibwa, Joseph; Majara, Lerato; Musinguzi, Henry; Mwema, Rehema M.; Neal, Benjamin M.; Newman, Carter P.; Newton, Charles R.J.C.; Pickrell, Joseph K.; Ramesar, Raj; Shiferaw, Welelta; Stein, Dan J.; Teferra, Solomon; Celia van der Merwe; Merwe, Celia van der; Zingela, Zukiswa; NeuroGAP-Psychosis Study Team (ALUPE UNIVERSITY, 2021-10-25)
    Genetic studies in underrepresented populations identify disproportionate numbers of novel associations. However, most genetic studies use genotyping arrays and sequenced reference panels that best capture variation most ...
  • Mosquitocidal Immune Response in BALB/c Mice Is Enhanced When Anopheles gambiae Mucin-1 cDNA Is Co-Administered with Interleukin-12 cDNA 
    Injera, Wilfred E.; Foy, Brian D.; Kabiru, Elphantus W.; Gicheru, Michael M.; Githure, John I.; Beier, John C. (Canadian Center of Science and Education, 2013)
    The midgut of the malaria - transmitting mosquito, Anopheles gambiae, can be targeted by vaccine-induced host immune factors that kill the mosquito after it ingests immunized host blood. The An. gambiae mucin 1 protein (AgMuc1) ...

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